Home                      Dipl.Chem.       Sigeng Han             

 

 

             Building N 160  Room B 413

                  Institute for organic chemistry 

                         Johann Wolfgang Goethe Universitšt

                     Max-von-Laue Str.7

                

 

 

                  

  

                    

 

                   

                  

 

                     60438 Frankfurt am Main

 

 

 

 

 

 

                     069-798 29165

         Fax: 069-798 29148

                   

                      S.Han@chemie.uni-frankfurt.de

             

   

From Streptomyces parvullus I cloned and sequenced a novel a-Amylase inhibitor coined Parvulustat. In Streptomyces parvullus the gene was expressed and using isotope enriched media we isolated a fully 15N and 13C Parvulustat. Mutagenesis experiments for folding and stability studies are being carried out.