Home                      Dipl.Chem.       Sigeng Han             



             Building N 160  Room B 413

                  Institute for organic chemistry 

                         Johann Wolfgang Goethe Universitšt

                     Max-von-Laue Str.7











                     60438 Frankfurt am Main







                     069-798 29165

         Fax: 069-798 29148





From Streptomyces parvullus I cloned and sequenced a novel a-Amylase inhibitor coined Parvulustat. In Streptomyces parvullus the gene was expressed and using isotope enriched media we isolated a fully 15N and 13C Parvulustat. Mutagenesis experiments for folding and stability studies are being carried out.